The height of Eisner's work, and one of the heights of comics art, was The Spirit, essentially an 8 page comic book distributed as a newspaper suppliment in the 40's and 50's. Don't let yourself be put off by what may seem at first to be an "old fashioned" comics style, this is the real thing.
I find a strong relationship between the "words and pictures in sequence telling a story" aspect of comics and the "words and pictures linked together in paths conveying information" nature of the Web, so I recommend this book to anyone interested in the Web, even though it never even mentions computers.